Background: Bronchopneumonia commonly occur as life threatening pneumonia manifestation in children. Antibiotics are frequently prescribed to treat bronchopneumonia. Inappropriate antibiotics usage can lead to bacterial resistance and inadequate treatments outcome. This study aimed to observe the appropriateness of antibiotics prescribed to outpatients children and adolescence bronchopneumonia.

Methods: Antibiotic prescriptions during 2016 at a Hospital in Bangkalan for outpatients children and adolescence age 0-14 y.o suffered from bronchopneumonia were asessed retrospectively for its appropriateness against British Thoracic Society guidelines through Gyssens Algorithm.

Results: There were 101 prescriptions for treating outpatients with broncopneumonia aged 0-14 y.o.. Of these, a total of 69 antibiotic prescriptions were included in this study. The most common prescribed antibiotics in the treatments were cephalosporins group and all of which were applied for empirical purposes. Of the 69 prescriptions analyzed, only 5 (7,25%) prescriptions were assessed as appropriate. All of inappropriate use of antibiotics was in the form of wrong drug of choice (100.00%).

Conclusion: Based on these results, related to the high of antibiotic prescriptions inappropriateness in Bronchopneumonia outpatients treatments, an improvement action in antibiotic prescribing to prevent antibiotic-associated problems like unnecessary adverse effects, treatment failure and bacterial resistance still need to be developed.

Key words: Antibiotics, Bronchopneumonia, Gyssen algorithm, Children, Adolescence

Kata Kunci

Key words: Antibiotics, Bronchopneumonia, Gyssen algorithm, Children, Adolescence.

Teks Lengkap:

PDF (English)


1. Ambroggio, L., Taylor, J.A., Tabb, L.P., Newscaffer, C.J., Evans, A.A., Shah, S.S., 2012, Comparative Effectiveness of Empiric β-lactam Monotherapy and β-lactam-Macrolide Combination Therapy in Children Hospitalized with Community-Acquired Pneumonia, J Pediatr, 161 (6), 1097–103.

Ambroggio, L., Test, M., Metlay, JP., Graf, T.R., Blosky M.A., Macaluso, M., Shah, S.S., 2015, Comparative Effectiveness of Beta-Lactam Versus Macrolide Monotherapy in Children with Pneumonia Diagnosed in The Outpatient Setting, Pediatr Infect Dis J, 34(8), 839–42.

Baktygul, K., Marat, B., Ashirali, Z., Harun-Or-Rashid, M.D., Sakamoto, J., 2011, An Assessment of Antibiotics Prescribed at the Secondary Health-care Level in the Kyrgyz Republic, Nagoya J Med Sci. 73(3-4):157-68.

Blyth, C.C., Gerber, J.S., 2018, Macrolides in Children with Community-acquired Pneumonia: Panacea or Placebo?, J Pediatric Infect Dis Soc., 19; 7(1), 71-77.

Goffinet, N., Lecadet, N., Cousin, M., Peron, C., Hardouin, J.B., Batard, E., Montassier E., 2014, Increasing Use of Third-generation Cephalosporins for Pneumonia in The Emergency Department: May Some Prescriptions be Avoided?, Eur J Clin Microbiol Infect Dis., 33 (7), 1095-9.

Farrell, D.J., File, T.M., Jenkins, S.G., 2007, Prevalence and Antibacterial Susceptibility of Mef (A)-positive Macrolide-resistant Streptococcus pneumoniae Over 4 years (2000 to 2004) of the PROTEKT US Study, J Clin Microbiol, 45 (2), 290-3.

Hariri, G., Tankovic, J., Boëlle, P., Dubée, V., Leblanc, G., Pichereau, C.,, 2017, Are Third-generation Cephalosporins Unavoidable for Empirical Therapy of Community-Acquired Pneumonia in Adult Patients Who Require ICU Admission? A Retrospective Study, Ann. Intensive Care, 7 (35), 1-8.

Harris, M., Clark, J., Coote, N., Fletcher, P., Harnden, A., McKean, M., et al., 2011, British Thoracic Society Guidelines for The Management of Community Acquired Pneumonia in Children: update 2011, Thorax, 66, ii1–ii23.

Kementerian Kesehatan Republik Indonesia, 2018, Profil kesehatan Indonesia tahun 2017, Kementerian Kesehatan Republik Indonesia, Jakarta.

United Nations Emergency Children's Fund. One is too many : ending child deaths from pneumonia and diarrhoea. The United Nations Children's Fund. Available at : . Acessed : 06 July 2019.

World Health Organization (WHO). Pneumonia. Available at: Accessed: 30 June 2019.

Zec, S.L., Selmanovic K., Andrijic, N.L., Kadic, A., Zecevic, L., Zunic, L., 2016, Evaluation of Drug Treatment of Bronchopneumonia at The Pediatric Clinic in Sarajevo, Med Arch, 70 (3), 177-181.



  • Saat ini tidak ada refbacks.

SCIENTIA Jurnal Farmasi dan Kesehatan

diterbitkan oleh STIFI Perintis Padang

Jl. Adinegoro km 17/Simp. Kalumpang Lubuk Buaya Padang – 25173

Telp. (0751) 482171  Fax. (0751)484522

    p-ISSN : 2087-5045                 e-ISSN : 2502-1834


This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.